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Prenylation of Rab8 GTPase by type I and type II geranylgeranyl transferases.

Rab GTPases are post-translationally modified by addition of geranylgeranyl moieties to carboxyl-terminal cysteine residues. For Rab proteins ending with xxCC xCxC and CCxx motifs this modification is catalysed by geranylgeranyltransferase type II (GGTaseII), and is entirely dependent on the Rab sub...

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Detalhes bibliográficos
Main Authors: Wilson, A L, Erdman, R A, Castellano, F, Maltese, W A
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219609/
https://ncbi.nlm.nih.gov/pubmed/9677305
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