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Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery

DNA double-strand breaks (DSBs) are among the most deleterious forms of DNA lesions in cells. Here we induced site-specific DSBs in yeast cells and monitored chromatin dynamics surrounding the DSB using Chromosome Conformation Capture (3C). We find that formation of a DSB within G1 cells is not suff...

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Hlavní autoři: Oza, Pranav, Jaspersen, Sue L., Miele, Adriana, Dekker, Job, Peterson, Craig L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675867/
https://ncbi.nlm.nih.gov/pubmed/19390086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1782209
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