Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA Double Strand Break Repair

Repair of DNA double strand breaks (DSBs) is key for maintenance of genome integrity. When DSBs are repaired by homologous recombination, DNA ends can undergo extensive processing, producing long stretches of single-stranded DNA (ssDNA). In vivo, DSB processing occurs in the context of chromatin, an...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Adkins, Nicholas L., Swygert, Sarah G., Kaur, Parminder, Niu, Hengyao, Grigoryev, Sergei A., Sung, Patrick, Wang, Hong, Peterson, Craig L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
DNA and Chromosomes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392674/
https://ncbi.nlm.nih.gov/pubmed/28202543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.776369
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