Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA Double Strand Break Repair

Repair of DNA double strand breaks (DSBs) is key for maintenance of genome integrity. When DSBs are repaired by homologous recombination, DNA ends can undergo extensive processing, producing long stretches of single-stranded DNA (ssDNA). In vivo, DSB processing occurs in the context of chromatin, an...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Adkins, Nicholas L., Swygert, Sarah G., Kaur, Parminder, Niu, Hengyao, Grigoryev, Sergei A., Sung, Patrick, Wang, Hong, Peterson, Craig L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
DNA and Chromosomes
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392674/
https://ncbi.nlm.nih.gov/pubmed/28202543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.776369
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