Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA Double Strand Break Repair

Repair of DNA double strand breaks (DSBs) is key for maintenance of genome integrity. When DSBs are repaired by homologous recombination, DNA ends can undergo extensive processing, producing long stretches of single-stranded DNA (ssDNA). In vivo, DSB processing occurs in the context of chromatin, an...

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Vydáno v:J Biol Chem
Hlavní autoři: Adkins, Nicholas L., Swygert, Sarah G., Kaur, Parminder, Niu, Hengyao, Grigoryev, Sergei A., Sung, Patrick, Wang, Hong, Peterson, Craig L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
DNA and Chromosomes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392674/
https://ncbi.nlm.nih.gov/pubmed/28202543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.776369
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