Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA Double Strand Break Repair

Repair of DNA double strand breaks (DSBs) is key for maintenance of genome integrity. When DSBs are repaired by homologous recombination, DNA ends can undergo extensive processing, producing long stretches of single-stranded DNA (ssDNA). In vivo, DSB processing occurs in the context of chromatin, an...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Adkins, Nicholas L., Swygert, Sarah G., Kaur, Parminder, Niu, Hengyao, Grigoryev, Sergei A., Sung, Patrick, Wang, Hong, Peterson, Craig L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392674/
https://ncbi.nlm.nih.gov/pubmed/28202543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.776369
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