Population pharmacokinetic modelling of aripiprazole and its active metabolite, dehydroaripiprazole, in psychiatric patients

AIMS: The aims of this study were to develop a combined population pharmacokinetic model for both aripiprazole and its active metabolite, dehydroaripiprazole, in psychiatric patients and to identify to what extent the genetic polymorphisms of cytochrome P450 (CYP) enzymes contribute to the variabili...

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Bibliografische gegevens
Hoofdauteurs: Kim, Jung-Ryul, Seo, Hyo-Bum, Cho, Joo-Youn, Kang, Do-Hyung, Kim, Yong Ku, Bahk, Won-Myong, Yu, Kyung-Sang, Shin, Sang-Goo, Kwon, Jun Soo, Jang, In-Jin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2008
Onderwerpen:
Pharmacokinetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675764/
https://ncbi.nlm.nih.gov/pubmed/19032724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03223.x
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