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Population pharmacokinetic modelling of aripiprazole and its active metabolite, dehydroaripiprazole, in psychiatric patients

AIMS: The aims of this study were to develop a combined population pharmacokinetic model for both aripiprazole and its active metabolite, dehydroaripiprazole, in psychiatric patients and to identify to what extent the genetic polymorphisms of cytochrome P450 (CYP) enzymes contribute to the variabili...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Kim, Jung-Ryul, Seo, Hyo-Bum, Cho, Joo-Youn, Kang, Do-Hyung, Kim, Yong Ku, Bahk, Won-Myong, Yu, Kyung-Sang, Shin, Sang-Goo, Kwon, Jun Soo, Jang, In-Jin
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Science Inc 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675764/
https://ncbi.nlm.nih.gov/pubmed/19032724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03223.x
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