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Neuronal protein trafficking associated with Alzheimer disease: From APP and BACE1 to glutamate receptors
Aberrant and/or cumulative amyloid-beta (Aβ) production, resulting from proteolytic processing of the amyloid precursor protein (APP) by β and γ-secretases, have been postulated to be a main etiological basis of Alzheimer disease (AD). A number of proteins influence the subcellular trafficking itine...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2009
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2675158/ https://ncbi.nlm.nih.gov/pubmed/19372755 |
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