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Surface Trafficking of APP and BACE in Live Cells
Amyloid‐β (Aβ)‐peptide, the major constituent of the plaques that develop during Alzheimer's disease, is generated via the cleavage of Aβ precursor protein (APP) by β‐site APP‐cleaving enzyme (BACE). Using live‐cell imaging of APP and BACE labeled with pH‐sensitive proteins, we could detect the...
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| Publicado no: | Traffic |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons A/S
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6680167/ https://ncbi.nlm.nih.gov/pubmed/25712587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12270 |
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