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Neuronal protein trafficking associated with Alzheimer disease: From APP and BACE1 to glutamate receptors

Aberrant and/or cumulative amyloid-beta (Aβ) production, resulting from proteolytic processing of the amyloid precursor protein (APP) by β and γ-secretases, have been postulated to be a main etiological basis of Alzheimer disease (AD). A number of proteins influence the subcellular trafficking itine...

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Bibliografske podrobnosti
Glavni avtor: Tang, Bor Luen
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675158/
https://ncbi.nlm.nih.gov/pubmed/19372755
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