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Activity-dependent depression of the spike after-depolarization generates long-lasting intrinsic plasticity in hippocampal CA3 pyramidal neurons

Persistent plastic changes to the intrinsic excitability of neurons have substantial implications for computational processing within the CNS. We have identified and characterized a novel long-lasting form of intrinsic plasticity in hippocampal CA3 pyramidal cells. Although the patterns of action po...

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Autores principales: Brown, Jon T, Randall, Andrew D
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674996/
https://ncbi.nlm.nih.gov/pubmed/19171653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.167007
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