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Alternative Induction of Meiotic Recombination From Single-Base Lesions of DNA Deaminases
Meiotic recombination enhances genetic diversity as well as ensures proper segregation of homologous chromosomes, requiring Spo11-initiated double-strand breaks (DSBs). DNA deaminases act on regions of single-stranded DNA and deaminate cytosine to uracil (dU). In the immunoglobulin locus, this lesio...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Genetics Society of America
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674839/ https://ncbi.nlm.nih.gov/pubmed/19237686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.101683 |
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