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Impact of Pregnancy-Associated Plasma Protein-A Deletion on the Adult Murine Skeleton
INTRODUCTION: The metalloproteinase, pregnancy-associated plasma protein-A (PAPP-A) functions to enhance local insulin-like growth factor (IGF)-I bioavailability through cleavage of inhibitory IGF binding proteins. Because IGF-I is an important regulator of skeletal growth and remodeling and PAPP-A...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Amer Soc Bone & Mineral Res.
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674540/ https://ncbi.nlm.nih.gov/pubmed/18086007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.071210 |
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