Leaky Cl(−)–HCO(3)(−) exchangers: cation fluxes via modified AE1

The abundant membrane protein AE1 normally functions as an obligate anion exchanger, with classical carrier properties, in human red blood cells. Recently, four single point mutations of hAE1 have been identified that have lost the anion exchange function, and act as non-selective monovalent cation...

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Bibliografiske detaljer
Main Authors: Ellory, J.C., Guizouarn, H., Borgese, F., Bruce, L.J., Wilkins, R.J., Stewart, G.W.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2008
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674097/
https://ncbi.nlm.nih.gov/pubmed/18957374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0154
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