Mice with a Targeted Disruption of the Cl(−)/HCO(3)(−) Exchanger AE3 Display a Reduced Seizure Threshold

Neuronal activity results in significant pH shifts in neurons, glia, and interstitial space. Several transport mechanisms are involved in the fine-tuning and regulation of extra- and intracellular pH. The sodium-independent electroneutral anion exchangers (AEs) exchange intracellular bicarbonate for...

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Main Authors: Hentschke, Moritz, Wiemann, Martin, Hentschke, Suna, Kurth, Ingo, Hermans-Borgmeyer, Irm, Seidenbecher, Thomas, Jentsch, Thomas J., Gal, Andreas, Hübner, Christian A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317631/
https://ncbi.nlm.nih.gov/pubmed/16354689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.1.182-191.2006
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