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Enhanced activity of human serotonin transporter variants associated with autism

Rare, functional, non-synonymous variants in the human serotonin (5-hydroxytryptamine, 5-HT) transporter (hSERT) gene (SLC6A4) have been identified in both autism and obsessive–compulsive disorder (OCD). Within autism, rare hSERT coding variants associate with rigid–compulsive traits, suggesting bot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Prasad, Harish C., Steiner, Jennifer A., Sutcliffe, James S., Blakely, Randy D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674096/
https://ncbi.nlm.nih.gov/pubmed/18957375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0143
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