NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo

NK cells use a variety of receptors to detect abnormal cells, including tumors and their metastases. However, in the case of melanoma, it remains to be determined what specific molecular interactions are involved and whether NK cells control metastatic progression and/or the route of dissemination....

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Hlavní autoři: Lakshmikanth, Tadepally, Burke, Shannon, Ali, Talib Hassan, Kimpfler, Silvia, Ursini, Francesco, Ruggeri, Loredana, Capanni, Marusca, Umansky, Viktor, Paschen, Annette, Sucker, Antje, Pende, Daniela, Groh, Veronika, Biassoni, Roberto, Höglund, Petter, Kato, Masashi, Shibuya, Kazuko, Schadendorf, Dirk, Anichini, Andrea, Ferrone, Soldano, Velardi, Andrea, Kärre, Klas, Shibuya, Akira, Carbone, Ennio, Colucci, Francesco
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673866/
https://ncbi.nlm.nih.gov/pubmed/19349689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36022
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