NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo

NK cells use a variety of receptors to detect abnormal cells, including tumors and their metastases. However, in the case of melanoma, it remains to be determined what specific molecular interactions are involved and whether NK cells control metastatic progression and/or the route of dissemination....

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Detalhes bibliográficos
Main Authors: Lakshmikanth, Tadepally, Burke, Shannon, Ali, Talib Hassan, Kimpfler, Silvia, Ursini, Francesco, Ruggeri, Loredana, Capanni, Marusca, Umansky, Viktor, Paschen, Annette, Sucker, Antje, Pende, Daniela, Groh, Veronika, Biassoni, Roberto, Höglund, Petter, Kato, Masashi, Shibuya, Kazuko, Schadendorf, Dirk, Anichini, Andrea, Ferrone, Soldano, Velardi, Andrea, Kärre, Klas, Shibuya, Akira, Carbone, Ennio, Colucci, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673866/
https://ncbi.nlm.nih.gov/pubmed/19349689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36022
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