Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans

Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of oxidized lipoproteins and apoptotic cells. Adaptive immune responses to various oxidation-specific epitopes play an important role in atherogenesis. However, accumulating evidence suggests that these epitopes are...

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Autors principals: Chou, Meng-Yun, Fogelstrand, Linda, Hartvigsen, Karsten, Hansen, Lotte F., Woelkers, Douglas, Shaw, Peter X., Choi, Jeomil, Perkmann, Thomas, Bäckhed, Fredrik, Miller, Yury I., Hörkkö, Sohvi, Corr, Maripat, Witztum, Joseph L., Binder, Christoph J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673862/
https://ncbi.nlm.nih.gov/pubmed/19363291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36800
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