Oxidation-Specific Epitopes are Danger Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity

Oxidation reactions are vital parts of metabolism and signal transduction. However, they also produce reactive oxygen species, which damage lipids, proteins and DNA, generating “oxidation-specific” epitopes. In this review, we will discuss the hypothesis that such common oxidation-specific epitopes...

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Bibliografski detalji
Glavni autori: Miller, Yury I., Choi, Soo-Ho, Wiesner, Philipp, Fang, Longhou, Harkewicz, Richard, Hartvigsen, Karsten, Boullier, Agnès, Gonen, Ayelet, Diehl, Cody J., Que, Xuchu, Montano, Erica, Shaw, Peter X., Tsimikas, Sotirios, Binder, Christoph J., Witztum, Joseph L.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075542/
https://ncbi.nlm.nih.gov/pubmed/21252151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.223875
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