Oxidation-Specific Epitopes are Danger Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity

Oxidation reactions are vital parts of metabolism and signal transduction. However, they also produce reactive oxygen species, which damage lipids, proteins and DNA, generating “oxidation-specific” epitopes. In this review, we will discuss the hypothesis that such common oxidation-specific epitopes...

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Detalhes bibliográficos
Main Authors: Miller, Yury I., Choi, Soo-Ho, Wiesner, Philipp, Fang, Longhou, Harkewicz, Richard, Hartvigsen, Karsten, Boullier, Agnès, Gonen, Ayelet, Diehl, Cody J., Que, Xuchu, Montano, Erica, Shaw, Peter X., Tsimikas, Sotirios, Binder, Christoph J., Witztum, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075542/
https://ncbi.nlm.nih.gov/pubmed/21252151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.223875
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