Ca(2+)-dependent induction of TRPM2 currents in hippocampal neurons

TRPM2 is a Ca(2+)-permeable member of the transient receptor potential melastatin family of cation channels whose activation by reactive oxygen/nitrogen species (ROS/RNS) and ADP-ribose (ADPR) is linked to cell death. While these channels are broadly expressed in the CNS, the presence of TRPM2 in ne...

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Detalhes bibliográficos
Main Authors: Olah, Michelle E, Jackson, Michael F, Li, Hongbin, Perez, Yaël, Sun, Hong-Shuo, Kiyonaka, Shigeki, Mori, Yasuo, Tymianski, Michael, MacDonald, John F
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673769/
https://ncbi.nlm.nih.gov/pubmed/19124544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.162289
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