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The effect of proteasome inhibitor MG132 on experimental inflammatory bowel disease
Immunoproteasome up-regulation enhances the processing of nuclear factor-κB (NF-κB) and degradation of IκBα, which correlates with increased amounts of NF-κB in the various cells. Aberrant activation of NF-κB is involved in the pathogenesis of inflammatory bowel disease (IBD). The aim of this study...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673755/ https://ncbi.nlm.nih.gov/pubmed/19220323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03872.x |
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