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Basic pharmacodynamic models for agents that alter the lifespan distribution of natural cells
A new class of basic indirect pharmacodynamic models for agents that alter the loss of natural cells based on a lifespan concept are presented. The lifespan indirect response (LIDR) models assume that cells (R) are produced at a constant rate (k(in)), survive during a certain duration T(R), and fina...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673548/ https://ncbi.nlm.nih.gov/pubmed/18551354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-008-9092-6 |
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