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Expression of mitochondrial regulatory genes parallels respiratory capacity and contractile function in a rat model of hypoxia-induced right ventricular hypertrophy

Chronic hypobaric hypoxia (CHH) increases load on the right ventricle (RV) resulting in RV hypertrophy. We hypothesized that CHH elicits distinct responses, i.e., the hypertrophied RV, unlike the left ventricle (LV), displaying enhanced mitochondrial respiratory and contractile function. Wistar rats...

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Autores principales: Zungu, Makhosazane, Young, Martin E., Stanley, William C., Essop, M. Faadiel
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673516/
https://ncbi.nlm.nih.gov/pubmed/18604475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-008-9867-5
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