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Expression of mitochondrial regulatory genes parallels respiratory capacity and contractile function in a rat model of hypoxia-induced right ventricular hypertrophy

Chronic hypobaric hypoxia (CHH) increases load on the right ventricle (RV) resulting in RV hypertrophy. We hypothesized that CHH elicits distinct responses, i.e., the hypertrophied RV, unlike the left ventricle (LV), displaying enhanced mitochondrial respiratory and contractile function. Wistar rats...

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Detalhes bibliográficos
Main Authors: Zungu, Makhosazane, Young, Martin E., Stanley, William C., Essop, M. Faadiel
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673516/
https://ncbi.nlm.nih.gov/pubmed/18604475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-008-9867-5
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