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Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment

Interactions between tumor and immune cells either enhance or inhibit cancer progression. We show here that Stat3 signaling within the tumor microenvironment induces a pro-carcinogenic cytokine, IL-23, while inhibiting a central anti-carcinogenic cytokine, IL-12, thereby shifting the balance of tumo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kortylewski, Marcin, Xin, Hong, Kujawski, Maciej, Lee, Heehyoung, Liu, Yong, Harris, Timothy, Drake, Charles, Pardoll, Drew, Yu, Hua
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673504/
https://ncbi.nlm.nih.gov/pubmed/19185846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.12.018
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