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Role of Fyn and PI3K in H(2)O(2)-induced inhibition of apical Cl(−)/OH(−) exchange activity in human intestinal epithelial cells

H(2)O(2) is a highly reactive oxygen metabolite that has been implicated as an important mediator of inflammation-induced intestinal injury associated with ischaemia/reperfusion, radiation and inflammatory bowel disease. Previous studies have shown that H(2)O(2) inhibits NaCl absorption and activate...

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Detalhes bibliográficos
Main Authors: SAKSENA, Seema, GILL, Ravinder K., TYAGI, Sangeeta, ALREFAI, Waddah A., RAMASWAMY, Krishnamurthy, DUDEJA, Pradeep K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673493/
https://ncbi.nlm.nih.gov/pubmed/18564062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070960
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