Mechanism underlying inhibition of intestinal apical Cl(–)/OH(–) exchange following infection with enteropathogenic E. coli

Enteropathogenic E. coli (EPEC) is a major cause of infantile diarrhea, but the pathophysiology underlying associated diarrhea is poorly understood. We examined the role of the luminal membrane Cl(–)/OH(–) exchange process in EPEC pathogenesis using in vitro and in vivo models. Cl(–)/OH(–) exchange...

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Detalhes bibliográficos
Main Authors: Gill, Ravinder K., Borthakur, Alip, Hodges, Kim, Turner, Jerrold R., Clayburgh, Daniel R., Saksena, Seema, Zaheer, Ayesha, Ramaswamy, Krishnamurthy, Hecht, Gail, Dudeja, Pradeep K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770946/
https://ncbi.nlm.nih.gov/pubmed/17256057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29625
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