Differential Presentation of Protein Interaction Surfaces on the Androgen Receptor Defines the Pharmacological Actions of Bound Ligands

The pharmacological activity of different nuclear receptor (NR) ligands is reflected by their impact on receptor structure. Thus, we asked whether differential presentation of protein-protein interaction surfaces on the androgen receptor (AR), a surrogate assay of receptor conformation, could be use...

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Detalhes bibliográficos
Main Authors: Norris, John David, Joseph, James David, Sherk, Andrea Barreto, Juzumiene, Dalia, Turnbull, Philip Stewart, Rafferty, Stephen William, Cui, Huaxia, Anderson, Erin, Fan, Daju, Dye, Delita Arnelle, Deng, Xiang, Kazmin, Dmitri, Chang, Ching-Yi, Willson, Tim Mark, McDonnell, Donald Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673463/
https://ncbi.nlm.nih.gov/pubmed/19389631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.01.016
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