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Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists

The impact of ligand binding on nuclear receptor (NR) structure and the ability of target cells to distinguish between different receptor-ligand complexes are key determinants of the pharmacological activity of NR ligands. However, until relatively recently, these mechanistic insights have not been...

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Autori principali: Joseph, James D., Wittmann, Bryan M., Dwyer, Mary A., Cui, Huaxia, Dye, Delita A., McDonnell, Donald P., Norris, John D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715477/
https://ncbi.nlm.nih.gov/pubmed/19574450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900185106
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