Biphasic Activation of p38MAPK Suggests That Apoptosis Is a Downstream Event in Pemphigus Acantholysis

In pemphigus vulgaris and pemphigus foliaceus (PF), autoantibodies against desmoglein-3 and desmoglein-1 induce epidermal cell detachment (acantholysis) and blistering. Activation of keratinocyte intracellular signaling pathways is emerging as an important component of pemphigus IgG-mediated acantho...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Lee, Hua En, Berkowitz, Paula, Jolly, Puneet S., Diaz, Luis A., Chua, Michael P., Rubenstein, David S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2009
Aiheet:
Mechanisms of Signal Transduction
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673318/
https://ncbi.nlm.nih.gov/pubmed/19270308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808204200
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia