Dynamic α-Helix Structure of Micelle-bound Human Amylin

Amylin is an endocrine hormone that regulates metabolism. In patients afflicted with type 2 diabetes, amylin is found in fibrillar deposits in the pancreas. Membranes are thought to facilitate the aggregation of amylin, and membrane-bound oligomers may be responsible for the islet β-cell toxicity th...

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Detalhes bibliográficos
Main Authors: Patil, Sharadrao M., Xu, Shihao, Sheftic, Sarah R., Alexandrescu, Andrei T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673267/
https://ncbi.nlm.nih.gov/pubmed/19244249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809085200
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