載入...

Differential Behavior of Missense Mutations in the Intersubunit Contact Domain of the Human Pyruvate Kinase M(2) Isozyme

In this study, we attempted to understand the mechanism of regulation of the activity and allosteric behavior of the pyruvate kinase M(2) enzyme and two of its missense mutations, H391Y and K422R, found in cells from Bloom syndrome patients, prone to develop cancer. Results show that despite the pre...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Akhtar, Kamal, Gupta, Vibhor, Koul, Anita, Alam, Neelima, Bhat, Rajiv, Bamezai, Rameshwar N. K.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673266/
https://ncbi.nlm.nih.gov/pubmed/19265196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808761200
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!