Novel Role of RanBP9 in BACE1 Processing of Amyloid Precursor Protein and Amyloid β Peptide Generation

Accumulation of the amyloid β (Aβ) peptide derived from the proteolytic processing of amyloid precursor protein (APP) is the defining pathological hallmark of Alzheimer disease. We previously demonstrated that the C-terminal 37 amino acids of lipoprotein receptor-related protein (LRP) robustly promo...

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Autors principals: Lakshmana, Madepalli K., Yoon, Il-Sang, Chen, Eunice, Bianchi, Elizabetta, Koo, Edward H., Kang, David E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Protein Synthesis, Post-Translational Modification, and Degradation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673255/
https://ncbi.nlm.nih.gov/pubmed/19251705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807345200
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