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Site-Directed Mutagenesis Reveals Putative Regions of Protein Interaction within the Transmembrane Domains of Connexins
Through cysteine scanning mutagenesis, we have compared sites within the transmembrane domains of two connexins, one from the α-class (Cx50) and one from the β-class (Cx32), where amino acid substitution disrupts the function of gap junction channels. In Cx32, eleven sites resulted in no channel fun...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673110/ https://ncbi.nlm.nih.gov/pubmed/18649182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15419060802013463 |
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