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Mutagenesis and Cysteine Scanning of Transmembrane Domain 10 of the Human Dipeptide Transporter

PURPOSE: The human dipeptide transporter (hPEPT1) facilitates transport of dipeptides and drugs from the intestine into the circulation. The role of transmembrane domain 10 (TMD10) of hPEPT1 in substrate translocation was investigated using cysteine-scanning mutagenesis with 2-Trimethylammonioethyl...

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Detalhes bibliográficos
Main Authors: Xu, Liya, Haworth, Ian S., Kulkarni, Ashutosh A., Bolger, Michael B., Davies, Daryl L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861424/
https://ncbi.nlm.nih.gov/pubmed/19685173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9952-9
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