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A conformational switch in the DiGIR1 ribozyme involved in release and folding of the downstream I-DirI mRNA
DiGIR1 is a group I-like cleavage ribozyme found as a structural domain within a nuclear twin-ribozyme group I intron. DiGIR1 catalyzes cleavage by branching at an Internal Processing Site (IPS) leading to formation of a lariat cap at the 5′-end of the 3′-cleavage product. The 3′-cleavage product is...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673072/ https://ncbi.nlm.nih.gov/pubmed/19329537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.669209 |
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