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The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

In budding yeast, the Pif1 DNA helicase is involved in the maintenance of both nuclear and mitochondrial genomes, but its role in these processes is still poorly understood. Here, we provide evidence for a new Pif1 function by demonstrating that its absence promotes genetic instability of alleles of...

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Détails bibliographiques
Auteurs principaux: Ribeyre, Cyril, Lopes, Judith, Boulé, Jean-Baptiste, Piazza, Aurèle, Guédin, Aurore, Zakian, Virginia A., Mergny, Jean-Louis, Nicolas, Alain
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673046/
https://ncbi.nlm.nih.gov/pubmed/19424434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000475
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