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Pif1 family helicases suppress genome instability at G-quadruplex motifs
The Saccharomyces cerevisiae Pif1 helicase is the prototypical member of the Pif1 DNA helicase family, which is conserved from bacteria to humans. We show that exceptionally potent G-quadruplex unwinding is conserved amongst Pif1 helicases. Moreover, Pif1 helicases from organisms separated by >3...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3680789/ https://ncbi.nlm.nih.gov/pubmed/23657261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12149 |
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