The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

In budding yeast, the Pif1 DNA helicase is involved in the maintenance of both nuclear and mitochondrial genomes, but its role in these processes is still poorly understood. Here, we provide evidence for a new Pif1 function by demonstrating that its absence promotes genetic instability of alleles of...

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Main Authors: Ribeyre, Cyril, Lopes, Judith, Boulé, Jean-Baptiste, Piazza, Aurèle, Guédin, Aurore, Zakian, Virginia A., Mergny, Jean-Louis, Nicolas, Alain
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673046/
https://ncbi.nlm.nih.gov/pubmed/19424434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000475
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