Germline Allele-Specific Expression of TGFBR1 Confers an Increased Risk of Colorectal Cancer

Much of the genetic predisposition to colorectal cancer (CRC) in humans is unexplained. Studying a Caucasian-dominated population in the United States, we showed that germline allele-specific expression (ASE) of the gene encoding transforming growth factor–β (TGF-β) type I receptor, TGFBR1, is a qua...

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Bibliographic Details
Main Authors: Valle, Laura, Serena-Acedo, Tarsicio, Liyanarachchi, Sandya, Hampel, Heather, Comeras, Ilene, Li, Zhongyuan, Zeng, Qinghua, Zhang, Hong-Tao, Pennison, Michael J., Sadim, Maureen, Pasche, Boris, Tanner, Stephan M., de la Chapelle, Albert
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672914/
https://ncbi.nlm.nih.gov/pubmed/18703712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1159397
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