Di(2-ethylhexyl) phthalate Is a Highly Potent Agonist for the Human Constitutive Androstane Receptor Splice Variant CAR2

The human constitutive androstane receptor (CAR, CAR1) regulates the expression of genes involved in xenobiotic metabolism in the liver. The CAR gene uses multiple alternative splicing events during pre-mRNA processing, thereby enhancing the CAR transcriptome. Previous reports have identified two pr...

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Detalhes bibliográficos
Main Authors: DeKeyser, Joshua G., Stagliano, Michael C., Auerbach, Scott S., Prabhu, K. Sandeep, Jones, A. Daniel, Omiecinski, Curtis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Accelerated Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672810/
https://ncbi.nlm.nih.gov/pubmed/19211671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.053702
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