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Structure-based discovery of β(2)-adrenergic receptor ligands
Aminergic G protein-coupled receptors (GPCRs) have been a major focus of pharmaceutical research for many years. Due partly to the lack of reliable receptor structures, drug discovery efforts have been largely ligand-based. The recently determined X-ray structure of the β(2)-adrenergic receptor offe...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672528/ https://ncbi.nlm.nih.gov/pubmed/19342484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812657106 |
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