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Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a
The microtubule depolymerase Kif2a controls spindle assembly and dynamics and is essential for chromosome congression and segregation. Through a proteomic analysis, we identified Kif2a as a target for regulation by the Polo-like kinase Plk1. Plk1 interacts with Kif2a, but only in mitosis, in a manne...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Company of Biologists
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671931/ https://ncbi.nlm.nih.gov/pubmed/19351716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.044321 |
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