A Vault Nanoparticle Vaccine Induces Protective Mucosal Immunity

BACKGROUND: Generation of robust cell-mediated immune responses at mucosal surfaces while reducing overall inflammation is a primary goal for vaccination. Here we report the use of a recombinant nanoparticle as a vaccine delivery platform against mucosal infections requiring T cell-mediated immunity...

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Detalhes bibliográficos
Main Authors: Champion, Cheryl I., Kickhoefer, Valerie A., Liu, Guangchao, Moniz, Raymond J., Freed, Amanda S., Bergmann, Liisa L., Vaccari, Dana, Raval-Fernandes, Sujna, Chan, Ann M., Rome, Leonard H., Kelly, Kathleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671841/
https://ncbi.nlm.nih.gov/pubmed/19404403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005409
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