APC dysfunction is correlated with defective suppression of T cell proliferation in human type 1 diabetes

It is widely believed that CD4(+)CD25(+) regulatory T cells (Treg) are defective in type 1 diabetes (T1D) and other autoimmune diseases. However, this conclusion is based on the suboptimal in vitro suppression results from very small numbers of subjects. Furthermore, the cells responsible for the su...

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Bibliographic Details
Main Authors: Jin, Yulan, Chen, Xueqin, Podolsky, Robert, Hopkins, Diane, Makala, Levi H. C., Muir, Andy, She, Jin-Xiong
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671725/
https://ncbi.nlm.nih.gov/pubmed/19036642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.10.005
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