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Over-expression of Stat5b confers protection against diabetes in the non-obese diabetic (NOD) mice via up-regulation of CD4(+)CD25(+) regulatory T cells

The signal transducers and activators of transcription (STAT) family of proteins play a critical role in cytokine signaling required for fine tuning of immune regulation. Previous reports showed that a mutation (L327M) in the Stat5b protein leads to aberrant cytokine signaling in the NOD mice. To fu...

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Bibliografski detalji
Glavni autori: Jin, Yulan, Purohit, Sharad, Chen, Xueqin, Yi, Bing, She, Jin-Xiong
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990414/
https://ncbi.nlm.nih.gov/pubmed/22789848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.06.162
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