APC dysfunction is correlated with defective suppression of T cell proliferation in human type 1 diabetes

It is widely believed that CD4(+)CD25(+) regulatory T cells (Treg) are defective in type 1 diabetes (T1D) and other autoimmune diseases. However, this conclusion is based on the suboptimal in vitro suppression results from very small numbers of subjects. Furthermore, the cells responsible for the su...

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Hlavní autoři: Jin, Yulan, Chen, Xueqin, Podolsky, Robert, Hopkins, Diane, Makala, Levi H. C., Muir, Andy, She, Jin-Xiong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671725/
https://ncbi.nlm.nih.gov/pubmed/19036642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.10.005
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