The Bacterial Virulence Factor Lymphostatin Compromises Intestinal Epithelial Barrier Function by Modulating Rho GTPases

Lymphocyte inhibitory factor A (lifA) in Citrobacter rodentium encodes the large toxin lymphostatin, which contains two enzymatic motifs associated with bacterial pathogenesis, a glucosyltransferase and a protease. Our aim was to determine the effects of each lymphostatin motif on intestinal epithel...

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Detalhes bibliográficos
Main Authors: Babbin, Brian A., Sasaki, Maiko, Gerner-Schmidt, Kirsten W., Nusrat, Asma, Klapproth, Jan-Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671366/
https://ncbi.nlm.nih.gov/pubmed/19286565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080640
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