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A Unique C-terminal Repeat Domain Maintains the Cytosolic Localization of the Placenta-specific Tristetraprolin Family Member ZFP36L3

Members of the tristetraprolin family of CCCH tandem zinc finger proteins bind to AU-rich elements in certain cellular mRNAs, leading to their deadenylation and destabilization. Studies in knock-out mice demonstrated roles for three of the family members, tristetraprolin, ZFP36L1, and ZFP36L2, in in...

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Detalhes bibliográficos
Main Authors: Frederick, Elizabeth D., Ramos, Silvia B. V., Blackshear, Perry J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671328/
https://ncbi.nlm.nih.gov/pubmed/18367448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801234200
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