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Improved spatial learning in aged rats by genetic activation of protein kinase C in small groups of hippocampal neurons

Age-related declines in human cognition are well known, and there are correlative changes in the function of neocortical and hippocampal neurons. Similarly, age-related declines in learning have been observed in rodents, including deficits in a hippocampal-dependent learning paradigm, the Morris wat...

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Detalhes bibliográficos
Main Authors: Zhang, Guo-rong, Liu, Meng, Cao, Haiyan, Kong, Lingxin, Wang, Xiaodan, O’Brien, Jennifer A., Wu, Shuo-chieh, Cook, Robert G., Geller, Alfred I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670945/
https://ncbi.nlm.nih.gov/pubmed/18942114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.20506
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