Targeted gene transfer to nigrostriatal neurons in the rat brain by helper virus-free HSV-1 vector particles that contain either a chimeric HSV-1 glycoprotein C-GDNF or a gC-BDNF protein

Direct gene transfer into neurons has potential for both studying neuronal physiology and for developing gene therapy treatments for specific neurological conditions. Due to the heterogeneous cellular composition of the brain, cell-type-specific recombinant gene expression is required for many poten...

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Hlavní autoři: Wang, Xiaodan, Kong, Lingxin, Zhang, Guo-rong, Sun, Mei, Geller, Alfred I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581866/
https://ncbi.nlm.nih.gov/pubmed/15993510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbrainres.2005.05.029
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